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Studies designed to provide insight into clinical practice in the real world are known as pragmatic trials. They are often characterized by their focus on practical aspects of study design that include recruitment and consent, adherence and the use routinely available equipment.

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A pragmatic study that involves a variety investigators and includes participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is required for practical trials to be valid, and it also helps reduce bias in the results. However too much heterogeneity could result in issues with the design of the trial.

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Pragmatic Play is renowned for its top-quality games and for providing a superior user experience. The software is available on mobile devices and in multiple languages. It has earned itself the status of one of the top gaming platforms for casinos despite its relative youth. The latest releases include Wolves which is a five-reel video slot that has a healthy RTP and impressive graphics. Its other notable titles are Wolf Gold and Chilli Heat.

Pragmatic trials aim to mimic real-life settings and 프라그마틱 추천 achieve maximum external validity. They are typically commissioned by practitioners and policy makers to aid in their decision-making. They also provide a useful way to identify the causality between the intervention and its effects. They should not, however be used to replace explanatory studies.

The pragmatism concept is controversial, and there are questions about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 proposed a distinction between explanatory studies, which confirm the physiological hypothesis or clinical hypothesis, and pragmatic trials, which inform the decision-making process for policy and practice. They also proposed the framework for pragmatic trials, called PRECIS.2 This tool attempted to define the elements of a practical trial that include recruitment, design and delivery of the intervention, as well as follow-up.

There is a growing increase in the number pragmatic trials that are published. A recent Medline search using the keywords pragmatic and naturalistic, restricted to randomized controlled trials (RCTs) produced 34 articles, shown in red in Figure 2. This is an indication that the health sciences community is becoming more acquaint to the issue of pragmatics. However, it is important to note that the majority of these studies were conducted in primary care settings.